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Natera, Aveta partner on late-stage head and neck cancer trial

By Thomson Reuters Jun 29, 2026 | 5:55 AM

June 29 (Reuters) – Genetic testing firm Natera and cancer drug developer Aveta Biomics said on Monday they ​have partnered on a late-stage ‌study of an experimental therapy for head and neck cancer, in a bid to improve how patients’ response to treatment is monitored.

Here ‌are ​some details:

• The ⁠study will test Aveta’s ⁠APG-157, an experimental oral therapy designed to help the body fight tumors, in patients with locally advanced head ​and neck cancer.

• Natera said its Signatera test will be used ⁠in the study to ⁠assess molecular residual disease and ​treatment response, and will serve as a ​secondary endpoint.

• The companies said the ‌test will be used before, during and after treatment to monitor patients’ response.

• Aveta Biomics said the study ⁠will enroll about 826 patients globally, including in North America, Europe, Asia-Pacific and Australia.

• It ⁠said ‌the study builds on data ⁠from a mid-stage trial showing ​the ‌therapy helped control tumors and ​showed encouraging ⁠survival outcomes.

• The trial is expected to begin enrollment in the second half of 2026, the companies said.

(Reporting by Sahil Pandey in Bengaluru; Editing by ​Diti Pujara)