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Pfizer CFO Dave Denton to leave company in August

By Thomson Reuters Jun 18, 2026 | 5:53 AM

By Padmanabhan Ananthan

June 18 (Reuters) – Pfizer said on Thursday that finance chief Dave Denton will leave on August 15 to return to the consumer goods industry, after ​helping the U.S. drugmaker navigate its post-COVID transition.

The company ‌named Cecile Guegan, senior vice president of finance for its global biopharmaceuticals business, as interim chief financial officer. Guegan has held a range of finance roles over 20 years at Pfizer.

Shares of the company were down 3.1% ‌at $25.1 ​in early trading.

Scotiabank analyst Louise Chen ⁠said Denton’s exit raises concerns ⁠among investors about the company’s 2026 forecast, succession plans and the timing of the move when Pfizer is preparing to enter the obesity drug market.

A FOUR-YEAR RUN

Denton, who succeeded ​long-time Pfizer finance chief Frank D’Amelio in 2022, joined from home-improvement chain Lowe’s Cos and was previously CFO at CVS ⁠Health, where he worked for nearly ⁠20 years.

His tenure at Pfizer coincided with an ​aggressive dealmaking phase as the company used the windfall from its ​COVID-19 vaccine and antiviral treatment to buy cancer-focused Seagen, ‌migraine drugmaker Biohaven and weight-loss treatment developer Metsera.

The deals aimed to soften the hit from declining sales of its COVID vaccine and antiviral treatment and prepare for looming patent expirations on key ⁠products.

CEO Albert Bourla has set a goal of adding $20 billion in revenue by 2030, but expects to return to growth after 2028.

The ⁠company’s shares have nearly ‌halved since Denton took over as CFO, ⁠as investors worried whether the acquisitions and internal ​drug ‌development programs can offset the revenue shortfall.

Despite the ​lingering concerns, ⁠shares had gained about 4% this year through Wednesday’s close.

Pfizer said it will conduct an internal and external search for a permanent successor.

Denton and Guegan will work together on the transition, the company said.

(Reporting by Padmanabhan Ananthan in Bengaluru; Editing by Vijay Kishore ​and Sriraj Kalluvila)