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Novavax pushes profitability target to 2029, shares dip

By Thomson Reuters Nov 5, 2026 | 7:04 AM

By Sriparna Roy

Nov 5 (Reuters) – Vaccine maker Novavax pushed back its target for reaching profitability to 2029 on Thursday, overshadowing an increase in its annual revenue forecast and ​sending its shares 9% lower.

The loss-making company had been ‌betting on a licensing agreement with French drugmaker Sanofi to make profits by 2028.

Sanofi’s flu-COVID combination vaccine would be the biggest driver of Novavax’s cash flow and the timeline for a late-stage trial is outside Novavax’s control, ‌B ​Riley analyst Mayank Mamtani said.

Sanofi intends to ⁠start the trial in ⁠2027, Novavax said. Novavax is eligible for a milestone payment of $225 million upon US commercial launch, which is expected in 2029.

Novavax has relied on licensing deals and partnerships tied to ​its protein-based vaccine platform and its Matrix-M adjuvant — a compound that boosts the body’s immune response to vaccines.

CEO John Jacobs ⁠told Reuters that Novavax is actively ⁠seeking more partnerships.

It is also aiming to build a ​library of data to expand the use of its vaccine technology ​and support potential partners’ vaccine programs.

“We view that library ‌as a strategic asset, and as the evidence grows, we believe so too does the potential for new and expanded partnerships,” said Bob Walker, head of research and development at Novavax, on ⁠a post-earnings call.

The Democrats’ sweep in the US midterm elections has lifted hopes of stability in vaccine policy after a period of uncertainty.

“I ⁠think it’s too ‌early to tell in the immediacy what may ⁠exactly happen there … I do think that could ​bode ‌well over time for vaccine manufacturers,” Jacobs said.

Novavax ​now expects ⁠2026 adjusted revenue between $385 million and $415 million, higher than $235 million to $275 million previously and analysts’ average estimate of $380.29 million, according to data compiled by LSEG.

Novavax posted a quarterly net loss of $31 million, narrowing from $202 million a year ago.

(Reporting by Sriparna Roy in Bengaluru; Editing ​by Sahal Muhammed)