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Gilead to buy PepStar’s inflammation drug program in $1.28 billion deal

By Thomson Reuters Oct 22, 2026 | 3:17 PM

Oct 22 (Reuters) – Gilead Sciences said on ​Thursday it ‌will acquire PepStar Therapeutics’ oral inflammation drug ‌program, ​including ⁠an experimental ⁠bowel disease treatment, for $1.275 billion in cash.

The ​deal will add ⁠HCXT-2001, an ⁠experimental oral ​drug for ​inflammatory bowel disease, to ‌Gilead’s portfolio.

The treatment acts on ⁠the IL-23 pathway, an established target ⁠for ‌inflammatory disease ⁠therapies.

HCXT-2001 is ​currently ‌in early-stage ​clinical testing.

(Reporting ⁠by Sahil Pandey in Bengaluru; Editing by Diti ​Pujara)