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Drug developer Lycia Therapeutics targets $938 million valuation in US IPO

By Thomson Reuters Oct 20, 2026 | 5:27 AM

Oct 20 (Reuters) – Drug developer Lycia Therapeutics said on Tuesday it was targeting a valuation of up to $937.7 million in its US initial ​public offering, as biotech companies flock to the ‌IPO market.

The South San Francisco, California-based company is seeking to raise up to $264.6 million in the IPO by offering 14.7 million shares priced between $16 and $18 apiece.

The healthcare sector has anchored ‌the ​fall IPO window this year in ⁠an otherwise lackluster market ⁠as investors become selective in a higher interest rate environment.

Drug developers City Therapeutics and Nvidia-backed Iambic Therapeutics went public in New York last week. Aspen ​Neuroscience and Bambusa Therapeutics also filed for US IPOs earlier this month.

“Smart investors pay attention to the ⁠lesser-known names as well. The ⁠recent filers tell us Q4 will ​have more deals than just Anthropic,” said Matt Kennedy, senior ​strategist at Renaissance Capital, a provider of IPO-focused ‌research and ETFs.

“Some of these small and mid-cap names could be tomorrow’s leaders.”

Lycia, which was founded by Nobel Prize winner Carolyn Bertozzi, is developing drugs to ⁠treat autoimmune, inflammatory and allergic diseases.

Its experimental drug, LCA-0061, is being developed in an early-stage trial to treat patients with ⁠food allergy.

The ‌firm has raised roughly $266.6 million from leading ⁠life sciences investors since its inception ​in 2019. ‌Its major shareholders include Versant Ventures, ​Venrock Healthcare, ⁠Redmile Group, RTW Investments, Janus Henderson, and Blue Owl.

Jefferies, TD Cowen, Evercore ISI, and Guggenheim Securities are joint book-running managers. Lycia will list on the Nasdaq under the symbol “LYCA”.

(Reporting by Arasu Kannagi Basil in Bengaluru; Editing ​by Devika Syamnath)