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HK-listed Metis TechBio, Eli Lilly strike drug-delivery deal worth up to $1.1 billion

By Thomson Reuters Oct 19, 2026 | 5:37 AM

Oct 19 (Reuters) – Hong Kong-listed Metis TechBio said on Monday it has entered into a collaboration ​agreement with Eli Lilly worth ‌up to $1.1 billion to research and develop tissue-specific drug delivery technologies.

The Chinese biotech will use its proprietary AI-driven drug-delivery platform ‌to ​develop next-generation technologies ⁠aimed at improving ⁠how LNP-based drugs reach target tissues.

Metis will be eligible to receive an upfront payment in the low ​double-digit millions US dollars and up to about $1.1 billion in development, ⁠regulatory and commercial ⁠milestone payments.

It will also be ​eligible for tiered royalties at a ​single-digit percentage of annual net sales ‌of products that are developed due to the collaboration.

The Chinese biotech will use its proprietary AI-driven ionizable ⁠lipid discovery and optimisation platform to develop delivery technologies aimed at improving the targeting ⁠and ‌biodistribution of LNP-based therapies.

Metis ⁠and Lilly aim to discover ​and ‌optimise novel LNP architectures that ​could ⁠improve tissue specificity and therapeutic performance, with potential applications across multiple disease areas.

(Reporting by Nikita Maria Jino and Kumar Tanishk in Bengaluru; Editing by ​Joyjeet Das)