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City Therapeutics eyes valuation of up to $956.3 million in US IPO amid biotech listing push

By Thomson Reuters Oct 9, 2026 | 6:16 AM

Oct 9 (Reuters) – City Therapeutics on Friday said it is targeting a valuation of up to $956.3 million in its US ​initial public offering, as biotech companies ‌press ahead with listings despite market uncertainty.

• The Massachusetts-based company is seeking to raise up to $184.7 million by offering 9.7 million shares priced between $17 and $19 ‌each

• ​The US IPO market has ⁠remained open for ⁠business, but uncertainty due to the Iran war and valuation concerns are forcing more attractive deal terms

• Even so, biotech companies ​are proceeding with IPOs on renewed investor interest, despite the overheated AI trade and ⁠geopolitical tensions

• Retension Pharmaceuticals ⁠upsized its IPO, while TRex Bio ​priced its offering on Thursday, with both drug ​developers expected to begin trading on Nasdaq ‌on Friday

• Nvidia-backed Iambic Therapeutics also launched its roadshow this week

• Founded in 2023, City Therapeutics is advancing a pipeline of ⁠RNA-based rare disease drugs

• Its lead candidate, CITY-FXI, is in early-stage trials to treat thrombosis, which is ⁠the formation ‌of harmful clots inside a ⁠blood vessel

• IPO proceeds will be ​used ‌to fund clinical trials, advance its ​RNA interference ⁠platform, and support working capital and general corporate purposes

• Goldman Sachs, Jefferies, Stifel and Oppenheimer are underwriters; shares will trade on Nasdaq as “CTY”

(Reporting by Prakhar Srivastava in Bengaluru; Editing by ​Vijay Kishore)