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RNA drug developer ADARx seeks $1.74 billion valuation in US IPO

By Thomson Reuters Sep 21, 2026 | 5:34 AM

Sept 21 (Reuters) – ADARx Pharmaceuticals is targeting a valuation of up to $1.74 billion in its US initial public offering, the company developing ​RNA drugs said on Monday.

The company ‌is aiming to raise up to $371.9 million by offering 21.9 million shares priced between $15 and $17.

A sharp rise in Treasury yields and higher interest rates, which kept some prospective ‌issuers ​on the sidelines, have not ⁠slowed the biotech sector.

Drug ⁠developers Retension Pharmaceuticals and TRex Bio filed for their listings on Friday, while Electra Therapeutics debuted after raising $350 million in an upsized IPO.

ADARx develops ​experimental RNA-based drugs for rare immune, kidney, cardiovascular and neurological diseases. RNA, short for ribonucleic ⁠acid, is a genetic molecule ⁠found in all cells.

Three of its ​programs are in clinical testing and two in advanced ​preclinical development.

Its most advanced candidate, onvuzosiran, is ‌in late-stage testing for hereditary angioedema, a rare genetic disorder that causes sudden swelling attacks.

The San Diego, California-based ADARx plans to use part of ⁠the IPO proceeds to fund late-stage trials and further research.

Drugmaker AbbVie has agreed to invest up to $100 million ⁠in a ‌concurrent private placement that would give ⁠it a roughly 4.9% stake in ​ADARx ‌following the IPO, ADARx said.

J.P. Morgan, ​Morgan Stanley, ⁠TD Cowen, UBS Investment Bank and LifeSci Capital are the underwriters for the offering.

It plans to list its shares on Nasdaq under the symbol “ADRX.”

(Reporting by Pragyan Kalita in Bengaluru; Editing by Joyjeet Das and ​Sahal Muhammed)