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BioNTech says lung cancer drug candidate prolonged lives in trial

By Thomson Reuters Sep 14, 2026 | 3:06 AM

FRANKFURT, Sept 14 (Reuters) – BioNTech said on Monday ​that a ‌late-stage trial showed its drug candidate gotistobart led ‌to ​a clinically ⁠meaningful overall ⁠survival benefit in a certain form of lung ​cancer compared with standard ⁠treatment.

It added ⁠that results ​from the PRESERVE-003 ​Phase 3 clinical trial ‌involved patients with squamous non-small cell lung ⁠cancer whose disease had progressed despite prior ⁠immunotherapy ‌and chemotherapy.

Gotistobart ⁠nearly doubled ​survival ‌compared with ​standard-of-care chemotherapy, ⁠the biotech firm said.

(Reporting by Ludwig Burger, editing by Thomas ​Seythal)