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Braveheart Bio targets $1.2 billion valuation in US IPO

By Thomson Reuters Jul 30, 2026 | 5:16 AM

July 30 (Reuters) – Braveheart Bio is targeting a valuation of up to $1.2 billion in its U.S. initial public offering, the clinical-stage biopharmaceutical ​company said on Thursday.

The San Francisco, California-based ‌company aims to raise $318.8 million in the IPO by offering 18.8 million shares priced between $15 and $17 each.

Biotech IPOs have staged a comeback in 2026, with analysts saying concerns ‌over ​stretched tech and AI valuations ⁠are driving capital into ⁠lagging sectors such as healthcare.

Braveheart Bio develops novel therapeutics for hypertrophic cardiomyopathy (HCM) and related cardiovascular diseases.

HCM is a condition where heart muscle becomes ​abnormally thickened, causing inefficient pumping and filling of blood that can lead to symptoms such ⁠as shortness of breath, chest ⁠pain, fatigue and fainting.

The company’s lead ​product, BHB‑1893, is an oral cardiac myosin inhibitor designed ​to treat obstructive and non-obstructive hypertrophic cardiomyopathy.

Cornerstone investor ‌Fidelity Management & Research has shown interest in purchasing up to $75 million in shares at the IPO price.

Since its inception in 2024, Braveheart has raised ⁠about $185 million in Series A financing from investors, including Andreessen Horowitz, Forbion and OrbiMed.

The company intends to use ⁠the proceeds to ‌advance the development of BHB-1893, for ⁠research and development as well as ​general ‌corporate purposes.

Goldman Sachs, Jefferies, TD Cowen, ​Stifel and ⁠Cantor are the joint bookrunners for the offering.

Braveheart Bio intends to list its shares on the Nasdaq Global Market under the symbol “BRVE”.

(Reporting by Pragyan Kalita in Bengaluru; Editing by Vijay Kishore, Shinjini Ganguli and ​Joyjeet Das)