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Insilico Medicine secures $2.75 billion drug collaboration with Eli Lilly

By Thomson Reuters Mar 29, 2026 | 6:15 AM

March 29 (Reuters) – Generative-AI drug developer Insilico Medicine said on Sunday it has agreed a global licensing and ​research deal with U.S. drugmaker Eli ‌Lilly, that could be worth up to $2.75 billion, including milestone payments.

Pharmaceutical companies are increasingly turning to AI to accelerate R&D, betting on new ‌modelling ​tools and automated labs ⁠to unlock efficiency ⁠gains across their pipeline, and in line with a push by the U.S. Food and Drug Administration to reduce animal ​testing in the near future.

Under the agreement, Lilly will receive an exclusive ⁠licence to develop, manufacture ⁠and commercialize preclinical oral drug ​candidates by Insilico Medicine for selected disease areas, ​the Hong Kong‑listed company said in ‌a regulatory filing.

Insilico Medicine also said that it will receive an upfront payment of $115 million and is eligible for development, ⁠regulatory and commercial milestone payments that could take the total deal value to about $2.75 billion, as ⁠well ‌as tiered royalties on future ⁠sales.

The Financial Times had earlier ​reported ‌on this deal. The newspaper, citing ​unnamed ⁠sources, said that Lilly will acquire exclusive rights to sell a GLP-1 drug for diabetes from Insilico Medicine.

(Reporting by Rishabh Jaiswal in Bengaluru; Editing by Mark Potter and ​Susan Fenton)