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China’s CSPC Pharmaceutical signs deal with AstraZeneca for weight-loss therapy

By Thomson Reuters Jan 29, 2026 | 7:35 PM

By Andrew Silver

SHANGHAI, Jan 30 (Reuters) – AstraZeneca will license experimental drugs for obesity and weight-related conditions from CSPC Pharmaceutical Group and collaborate on additional ‍projects, paying $1.2 billion upfront and up to $17.3 billion more if development and sales milestones are met, the Chinese drugmaker said on Friday.

The deal is the latest tie-up between the two pharmaceutical giants, following collaboration in areas such as artificial intelligence. ‌It expands AstraZeneca’s investment in the ‌growing obesity market led by Western rivals.

The British-Swedish drugmaker has also licensed an experimental weight-loss pill from China’s EccoGene.

CSPC shares were down about 12% in Hong Kong following the announcement.

“This reflects ​the classic ‘buy the rumour, sell the news’ phenomenon,” said Tony Ren, head of Asia healthcare research at ‍Macquarie Capital, adding that investors ​seemed to be offloading the stock after ​its 26% surge since January 2.

The newly licensed drug candidates ‍from CSPC include SYH2082, a “clinical-ready” product, and three other pre-clinical products in its injectable weight-management portfolio, the company said in a filing to the Hong Kong Stock Exchange.

The agreement covers the development, manufacturing and commercialisation ‍of the candidates. AstraZeneca has been granted a global licence, excluding Taiwan, Hong Kong, Macau, and mainland China.

AstraZeneca will also collaborate ‍on four ‍additional new programmes with CSPC, using CSPC’s ​proprietary platforms for sustained-release delivery technology and ​AI-driven ⁠peptide drug discovery.

A spokesperson for AstraZeneca said ‌in a statement the new CSPC Pharmaceutical deal was in addition to a previous $15 billion investment in China that it announced on Thursday.

(Reporting by Sherin Sunny in Bengaluru and Andrew Silver in Shanghai; Editing by Rashmi Aich, William Mallard ⁠and Sherry Jacob-Phillips)