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China’s Qyuns Therapeutics licenses antibody program to Caldera in up to $780 million deal

By Thomson Reuters Nov 5, 2026 | 7:59 AM

Nov 5 – Qyuns Therapeutics is licensing an early-stage antibody program to US biotech ​Caldera Therapeutics in a ‌deal worth up to $750 million plus an upfront fee, the Hong Kong-listed firm said on Thursday.

Here are some ‌details:

• ​Caldera gets exclusive ⁠worldwide rights to ⁠develop, manufacture, seek approval for and sell drug candidates from the program, while Qyuns will ​receive $30 million upfront, plus up to $750 million tied to ⁠development, regulatory and ⁠commercial milestones

• The Jiangsu-headquartered ​company will also get tiered royalties ​on net sales for a ‌set period after a product first goes on sale

• The program covers antibodies designed to ⁠block two immune-related targets, TL1A and IL-17

• The deal adds to Qyuns’ growing ⁠track ‌record of out-licensing, following ⁠a milestone payment it ​received ‌from Roche in May ​after the ⁠first participant was dosed in a Phase 1 trial of a separate drug

(Reporting by Rudrannsh Mehra in Bengaluru; Editing by ​Vijay Kishore)