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AstraZeneca, Daiichi Sankyo partner with Summit to test cancer drug combination

By Thomson Reuters Oct 2, 2026 | 1:58 AM

Oct 2 (Reuters) – Summit Therapeutics on Friday announced a clinical trial collaboration with AstraZeneca and Daiichi Sankyo to test ​their cancer drug Datroway in combination with ‌Summit’s ivonescimab across multiple tumour types, including lung and breast cancers.

Here are more details:

• The companies said that they intend to begin with a late-stage ‌trial ​testing the therapies in first-line ⁠triple-negative breast cancer

• “This ⁠collaboration represents an important expansion of Summit’s global development program into breast cancer and a path for additional solid tumor settings,” ​said Maky Zanganeh, co-CEO of Summit Therapeutics

• The deal builds on AstraZeneca’s $2 billion investment ⁠in Summit earlier this ⁠week to collaborate on a ​series of studies testing their cancer treatments together

• ​Under the latest agreement, each company will ‌contribute its respective medicine and share trial costs, while retaining development and commercial rights to their own drugs

• The announcement provides ⁠further colour on the intentions for the Summit collaboration, Barclays analyst James Gordon said, adding that ⁠lung was ‌a clear strength for ivonescimab and could ⁠partner well with AstraZeneca’s lung ​portfolio

• “While ‌the collaboration formally begins with a ​phase three ⁠first-line triple-negative breast cancer study, we see the biggest potential opportunity in non-small cell lung cancer,” Gordon said

(Reporting by Nithyashree R B and Sneha S K in Bengaluru; Editing by ​Mrigank Dhaniwala)