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S&P 500, Dow set for higher open with focus on Mideast developments

By Thomson Reuters Sep 22, 2026 | 5:19 AM

By Johann M Cherian and Tharuniyaa Lakshmi

Sept 22 (Reuters) – The benchmark S&P 500 and the blue-chip Dow were set for a modestly higher open on Tuesday as investors awaited potential talks between the United States and Iran that could end their six-month-old conflict.

Investors weighed ​comments by a senior Iranian official to Reuters that Tehran could reopen the Strait ‌of Hormuz within seven days if the US eases pressure. Saudi Arabia also restarted operations at its East-West Pipeline, according to three sources.

Brent crude eased 1.7% following the latest developments, but was still within reaching distance of $100 a barrel, while the yield on the benchmark 10-year Treasury note was at 4.9% – both hovering near levels that spurred market direction in ‌recent ​days.

“Markets are really seeing oil as the key macro variable here, ⁠where both interest rates and the ⁠broader market are very much correlated to what’s happening in oil and on the geopolitical front,” said Lale Akoner, global market strategist at eToro.

US-Iran talks are expected on the sidelines of this week’s United Nations General Assembly meeting, followed by a US-China summit on Thursday. Traders hope it ​will yield a resolution on the Middle East conflict and extend the trade truce with Beijing. President Donald Trump is also scheduled to meet several world leaders later in the day.

At 08:29 a.m. ⁠ET, Dow E-minis were up 208 points, or 0.4%, and ⁠S&P 500 E-minis were up 6 points, or 0.08%. Nasdaq 100 E-minis were ​down 8 points, or 0.03%.

SPOTLIGHT ON MAG 7

The tech-heavy Nasdaq closed at a record high on Monday, driven ​by an 11.3% jump in Meta as analysts pointed to its Muse AI ‌agent garnering more downloads in its first 13 days than ChatGPT.

In premarket trading, Meta eased 0.5%, while Alphabet climbed 0.4%, Amazon.com edged up 0.1% and Microsoft inched up 1.1%. Salesforce also rose 1.6% and led gains among Dow components.

On the flip side, chip stocks that have been the biggest beneficiaries of the AI ⁠trade this year were lower: Nvidia eased 0.2% and US-listed shares of TSMC and SK Hynix lost around 1% each.

“The market got credible confirmation that its monetization is on track with its AI agent, which ⁠has boosted confidence that Meta could ‌finally be turning its huge AI spending into products that consumers will ⁠use,” said Akoner.

Federal Reserve policymakers consider AI demand and the oil shock ​as key ‌inflation drivers. Traders now see a 53.1% chance the central bank will ​increase interest ⁠rates by at least 25 basis points in October, following this month’s hike, the CME Group’s FedWatch Tool showed.

Remarks from at least three central bankers — Fed Vice Chair Philip Jefferson, New York Fed President John Williams and Richmond Fed President Thomas Barkin — are expected later in the day.

Among others, bitcoin retreated 1% from a seven-month high, dragging crypto stocks Strategy and Coinbase lower.

(Reporting by Johann M Cherian in Bengaluru; Editing by ​Joyjeet Das and Devika Syamnath)