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Viking Therapeutics’ obesity drug shows durable weight-loss benefit, shares jump

By Thomson Reuters Sep 22, 2026 | 6:13 AM

Sept 22 (Reuters) – Viking Therapeutics said patients shifted to a less ​frequent dosing regimen ‌of its experimental obesity treatment showed superior weight loss maintenance in a study ‌than ​those on ⁠placebo, sending its ⁠shares up 40% before the bell.

The company said on Tuesday that ​patients who switched to an every-other-week dosing ⁠of VK2735 ⁠maintained up to ​97% of the weight they ​had lost during an ‌initial 21-week treatment period, while those who moved to a monthly ⁠dosing retained up to 90% of their prior weight ⁠loss ‌over the following ⁠12 weeks.

Viking said ​it ‌plans to study oral ​maintenance ⁠dosing in a future part of the trial.

(Reporting by Padmanabhan Ananthan in Bengaluru; Editing by Shinjini ​Ganguli)