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Charles River lifts profit forecast on improving biotech demand

By Thomson Reuters Aug 5, 2026 | 6:37 AM

By Puyaan Singh

Aug 5 (Reuters) – Charles River Laboratories raised its annual profit forecast on Wednesday after the contract drug developer beat quarterly profit and revenue estimates on ​stronger demand for its drug discovery and development ‌services from biotechs.

Shares of the company were up 11.6% at $261.37.

Clinical research organizations have shown signs of improvement as biotech and pharmaceutical companies increase spending on research and manufacturing after a prolonged post-pandemic slowdown.

Here are more details:

• “We ‌were ​encouraged that the demand environment continued to ⁠strengthen in the second ⁠quarter … this improvement was broad based across our global biopharmaceutical and small and mid-sized biotechnology clients,” said CEO Birgit Girshick.

• The Wilmington, Massachusetts-based company now expects its 2026 adjusted ​per-share profit to be between $11.15 and $11.45, up from its prior view of $10.80 to $11.30.

• Charles River said the new forecast “reflects ⁠the expected operational outperformance for the ⁠year, including in the second quarter,” primarily driven ​by improving demand trends in the drug discovery and safety assessment ​segment and better-than-expected performance in manufacturing.

• Girshick said AI ‌should boost Charles River’s demand by generating more drug development programs needing validation and safety testing, though material impact may take one or two years to reflect.

• She also said the ⁠company is seeing a shift to more pre-clinical drug research work, adding it will lead to later-stage, more specialty work.

• Quarterly revenue ⁠in its drug ‌discovery and safety assessment segment rose 0.2% ⁠on an organic basis to $606.5 million, helped by ​higher ‌study volumes for regulated safety assessment services.

• Charles ​River’s second-quarter ⁠revenue came in at $1 billion, surpassing analysts’ average estimate of $975.7 million, according to data compiled by LSEG.

• On an adjusted basis, Charles River reported profit of $3.02 per share, beating Wall Street’s estimate of $2.74.

(Reporting by Puyaan Singh in Bengaluru; Editing by Tasim Zahid ​and Shinjini Ganguli)