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Obesity biotech Kalohexis confidentially files to go public in US

By Thomson Reuters Jul 7, 2026 | 7:50 AM

July 7 (Reuters) – Obesity-focused clinical-stage biotechnology company Kalohexis on Tuesday confidentially filed to go public in ​the U.S., adding to ‌an activity rebound in the initial public offering market.

Terms of the offering were not yet determined, the company said.

Here are ‌more ​details about the ⁠company:

• Kalohexis launched ⁠after spinning out of Endevica Bio in March, to advance the clinical development of its portfolio drug ​candidates. The Endevica Bio leadership team leads this new company.

• ⁠Kalohexis aims to ⁠treat metabolic disorders by targeting ​the body’s melanocortin (MC) system, a natural ​regulator of metabolic homeostasis.

• The company ‌is developing a proprietary pipeline of peptides designed to safely target these central regulatory receptors.

• Its ⁠lead program, 710GO, is an oral dual MC3/MC4 receptor agonist intended to induce durable ⁠weight ‌loss for general obesity.

• ⁠Additionally, the company is advancing ​mifomelatide, ‌a dual MC3R/MC4R antagonist ​designed to ⁠combat cachexia, a severe wasting syndrome that can become life threatening, in patients with advanced cancers.

(Reporting by Pritam Biswas in Bengaluru; Editing by ​Shreya Biswas)