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Natera, Aveta partner on late-stage head and neck cancer trial

By Thomson Reuters Jun 29, 2026 | 5:55 AM

By Sahil Pandey

June 29 (Reuters) – Genetic testing firm Natera and cancer drug developer Aveta Biomics said on Monday they have partnered on a late-stage ​study of an experimental therapy for head ‌and neck cancer, in a bid to improve how patients’ response to treatment is monitored.

Shares of Natera were up about 2% in morning trading.

Here are some details:

• The study will ‌test ​Aveta’s APG-157, an experimental oral ⁠therapy designed to help ⁠the body fight tumors, in patients with locally advanced head and neck cancer.

• Natera said its Signatera test will be used in the study to ​assess molecular residual disease and treatment response, and will serve as a secondary endpoint.

• “This represents yet ⁠another cancer type that is ⁠validating Signatera as likely having a ​material use case in the clinic for patients,” Evercore ISI ​analyst Daniel Markowitz said.

• “We continue to see ‌a growing body of evidence that suggests Signatera is on its way to gaining traction in the large and underpenetrated cancer monitoring market,” Markowitz added

• The ⁠companies said the test will be used before, during and after treatment to monitor patients’ response.

• Aveta Biomics said ⁠the study will ‌enroll about 826 patients globally, including ⁠in North America, Europe, Asia-Pacific and ​Australia.

• It ‌said the study builds on data ​from a ⁠mid-stage trial showing the therapy helped control tumors and showed encouraging survival outcomes.

• The trial is expected to begin enrollment in the second half of 2026, the companies said.

(Reporting by Sahil Pandey in Bengaluru; Editing ​by Diti Pujara)