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Drug developer Generate Biomedicines raises $400 million in US IPO

By Thomson Reuters Feb 26, 2026 | 7:11 PM

Feb 26 (Reuters) – Generate Biomedicines said on Thursday that it raised $400 million in its U.S. initial public offering, pricing shares ​of the U.S.-based drug developer ‌at $16 each.

The offering comes as the IPO market remains volatile, with swings in high-growth technology stocks driven by concerns that artificial intelligence could disrupt ‌established ​businesses and industries.

Recent sell-offs ⁠have delayed IPO plans ⁠of several firms, with analysts noting that successful listings generally depend on strong investor sentiment.

Backed by venture firm Flagship ​Pioneering, Generate Biomedicines sold 25 million shares in the offering, within its target ⁠range of $15 to $17, with ⁠all shares offered by the ​company itself.

Founded by Flagship in 2018, Generate Biomedicines ​uses AI-driven technology to move beyond ‌traditional trial-and-error drug discovery and develop new protein-based therapies, with its pipeline centered on immunology and oncology.

Generate’s lead drug candidate for ⁠severe asthma, GB-0895, is currently in a late-stage trial, with full enrollment in the study expected ⁠by ‌the first half of 2028.

The ⁠company will start trading on the ​Nasdaq ‌under the ticker symbol “GENB” on ​Friday.

Goldman Sachs, ⁠Morgan Stanley, Piper Sandler, Guggenheim Securities and Cantor are the underwriters for the offering.

(Reporting by Manya Saini in Bengaluru and Natalia Bueno Rebolledo in Mexico City; Editing by ​Sherry Jacob-Phillips)