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Novartis expects low single-digit decline in 2026 operating profit

By Thomson Reuters Feb 4, 2026 | 12:12 AM

FRANKFURT, Feb 4 (Reuters) – Swiss drugmaker Novartis forecast a decline in 2026 operating profit ‍in the low single-digit percentage range on Wednesday, held back by competition from cheaper copies of established products such as heart ‌drug Entresto.

It also reported ‌a 1% gain in fourth-quarter operating profit, which is adjusted for special items, on higher sales of breast ​cancer drug Kisqali, multiple sclerosis drug Kesimpta and ‍psoriasis drug Cosentyx, ​among other drugs.

The profit ​figure came in at $4.92 billion, in ‍line with an analyst consensus of about $4.9 billion, compiled by Visible Alpha.

Novartis is leaning on fast-growing cancer drugs Kisqali ‍and Scemblix and its $30 billion acquisition and licensing push last year to address ‍the ‍impending patent cliff ​for some of its ​blockbuster ⁠drugs, including Entresto for ‌heart failure, allergy shot Xolair and Cosentyx.

(Reporting by Ludwig Burger in Frankfurt and Bhanvi Satija in London; Editing by Emelia Sithole-Matarise and ⁠Linda Pasquini)