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Gilead’s experimental HIV treatment meets main goal in late-stage trial

By Thomson Reuters Dec 15, 2025 | 7:43 AM

Dec 15 (Reuters) – Gilead Sciences said on Monday its experimental HIV ‍treatment met the main goal in a late-stage trial.

The treatment regimen could expand treatment options and ‌help people with ‌HIV maintain long-term control of the virus, the company said.

In the study, a once-daily, single-tablet ​combination of bictegravir and lenacapavir was ‍as effective ​as Gilead’s existing HIV ​pill Biktarvy in patients ‍whose virus was already suppressed.

Bictegravir is a widely recommended HIV drug known as an integrase ‍strand transfer inhibitor and is used only in combination with ‍other ‍antiretroviral medicines.

Lenacapavir is ​approved in several ​countries ⁠to prevent sexually ‌acquired HIV in adults and adolescents at risk of infection.

(Reporting by Sriparna Roy in Bengaluru; Editing by Tasim ⁠Zahid)